7P30

3.0 A resolution structure of a DNA-loaded MCM double hexamer

This is a non-PDB format compatible entry.

Summary for 7P30

• Entry DOI: 10.2210/pdb7p30/pdb
• EMDB information: 13176
• Descriptor: DNA replication licensing factor MCM2, MAGNESIUM ION, ZINC ION, ... (12 entities in total)
• Functional Keywords: mcm2-7 helicase, nucleoprotein complex, aaa+ atpase, dna replication, replication
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 14
• Total formula weight: 1258862.96

Authors

Greiwe, J.F.,Miller, T.C.R.,Martino, F.,Costa, A. (deposition date: 2021-07-06, release date: 2022-02-02)

• Primary citation: Greiwe, J.F.,Miller, T.C.R.,Locke, J.,Martino, F.,Howell, S.,Schreiber, A.,Nans, A.,Diffley, J.F.X.,Costa, A.; Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase.; Nat.Struct.Mol.Biol., 29:10-20, 2022; PubMed: 34963704; DOI: 10.1038/s41594-021-00698-z

Experimental method

ELECTRON MICROSCOPY (3 Å)