7P0X

Crystal structure of Thioredoxin reductase from Brugia Malayi

Summary for 7P0X

• Entry DOI: 10.2210/pdb7p0x/pdb
• Descriptor: Glutaredoxin domain-containing protein, FLAVIN-ADENINE DINUCLEOTIDE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (7 entities in total)
• Functional Keywords: glutaredoxin, flavoprotein, selenocysteine, oxidoreductase
• Biological source: Brugia malayi (Filarial nematode worm); More
• Total number of polymer chains: 3
• Total formula weight: 201155.85

Authors

Fata, F.,Ardini, M.,Silvestri, I.,Gabriele, F.,Cheng, Q.,Arner, E.S.J.,Williams, D.L. (deposition date: 2021-06-30, release date: 2022-04-06, Last modification date: 2024-01-31)

• Primary citation: Fata, F.,Gencheva, R.,Cheng, Q.,Lullo, R.,Ardini, M.,Silvestri, I.,Gabriele, F.,Ippoliti, R.,Bulman, C.A.,Sakanari, J.A.,Williams, D.L.,Arner, E.S.J.,Angelucci, F.; Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus.; Redox Biol, 51:102278-102278, 2022; PubMed: 35276442; DOI: 10.1016/j.redox.2022.102278

Experimental method

X-RAY DIFFRACTION (2.55 Å)