7OYP
Carbonic anhydrase II in complex with Hit3-t1 (MH172)
Summary for 7OYP
| Entry DOI | 10.2210/pdb7oyp/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, (2S)-3-oxidanyl-2-[2-[(4-sulfamoylphenyl)methoxyamino]ethanoylamino]propanamide, ... (5 entities in total) |
| Functional Keywords | carbonic anhydrase, inhibitor, lyase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29872.05 |
| Authors | Kugler, M.,Brynda, J.,Rezacova, P. (deposition date: 2021-06-24, release date: 2023-01-18, Last modification date: 2024-02-07) |
| Primary citation | Kugler, M.,Hadzima, M.,Dzijak, R.,Rampmaier, R.,Srb, P.,Vrzal, L.,Voburka, Z.,Majer, P.,Rezacova, P.,Vrabel, M. Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. Rsc Med Chem, 14:144-153, 2023 Cited by PubMed: 36760748DOI: 10.1039/d2md00330a PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.05 Å) |
Structure validation
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