7OYO
Carbonic anhydrase II in complex with Hit4 (MH70)
Summary for 7OYO
| Entry DOI | 10.2210/pdb7oyo/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, [1-[2-oxidanylidene-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]-1,2,3-triazolidin-4-yl]methyl hydrogen carbonate, ... (5 entities in total) |
| Functional Keywords | carbonic anhydrase, inhibitor, lyase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29820.02 |
| Authors | Kugler, M.,Brynda, J.,Rezacova, P. (deposition date: 2021-06-24, release date: 2023-01-18, Last modification date: 2024-02-07) |
| Primary citation | Kugler, M.,Hadzima, M.,Dzijak, R.,Rampmaier, R.,Srb, P.,Vrzal, L.,Voburka, Z.,Majer, P.,Rezacova, P.,Vrabel, M. Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. Rsc Med Chem, 14:144-153, 2023 Cited by PubMed: 36760748DOI: 10.1039/d2md00330a PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.03 Å) |
Structure validation
Download full validation report
