7OVT

major seeded in vitro fibril morphology from murine SAA1.1 protein

Summary for 7OVT

Entry DOI	10.2210/pdb7ovt/pdb
EMDB information	13089 8910
Descriptor	Serum amyloid A-2 protein (1 entity in total)
Functional Keywords	systemic amyloidosis, seeded, misfolding disease, inflammation, prion, protein fibril
Biological source	Mus musculus (house mouse)
Total number of polymer chains	12
Total formula weight	139471.55
Authors	Heerde, T.,Schmidt, M.,Faendrich, M. (deposition date: 2021-06-15, release date: 2022-02-02)
Primary citation	Heerde, T.,Rennegarbe, M.,Biedermann, A.,Savran, D.,Pfeiffer, P.B.,Hitzenberger, M.,Baur, J.,Puscalau-Girtu, I.,Zacharias, M.,Schwierz, N.,Haupt, C.,Schmidt, M.,Fandrich, M. Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding. Nat Commun, 13:85-85, 2022 Cited by PubMed: 35013242 DOI: 10.1038/s41467-021-27688-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.69 Å)

Structure validation