7O50

Crystal structure of human legumain in complex with Gly-Ser-Asn peptide

Summary for 7O50

• Entry DOI: 10.2210/pdb7o50/pdb
• Descriptor: Legumain, GLY-SER-ASN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: enzyme, cysteine protease, ligase, asparaginyl endopeptidase, substrate, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 62209.35

Authors

Dall, E.,Brandstetter, H. (deposition date: 2021-04-07, release date: 2021-09-22, Last modification date: 2024-01-31)

• Primary citation: Dall, E.,Stanojlovic, V.,Demir, F.,Briza, P.,Dahms, S.O.,Huesgen, P.F.,Cabrele, C.,Brandstetter, H.; The Peptide Ligase Activity of Human Legumain Depends on Fold Stabilization and Balanced Substrate Affinities.; Acs Catalysis, 11:11885-11896, 2021; PubMed: 34621593; DOI: 10.1021/acscatal.1c02057

Experimental method

X-RAY DIFFRACTION (1.9 Å)