7NUH

Influenza A/California/07/2009(H1N1) endonuclease with I38T mutation in complex with orientin

Summary for 7NUH

• Entry DOI: 10.2210/pdb7nuh/pdb
• Descriptor: Polymerase acidic protein,Polymerase acidic protein, MANGANESE (II) ION, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: endonuclease, protein-ligand complex, rna polymerase, flavonoids, viral protein
• Biological source: Influenza A virus (A/California/07/2009(H1N1)); More
• Total number of polymer chains: 1
• Total formula weight: 22239.20

Authors

Radilova, K.,Brynda, J. (deposition date: 2021-03-12, release date: 2021-07-28, Last modification date: 2024-01-31)

• Primary citation: Reiberger, R.,Radilova, K.,Kral, M.,Zima, V.,Majer, P.,Brynda, J.,Dracinsky, M.,Konvalinka, J.,Kozisek, M.,Machara, A.; Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.; Int J Mol Sci, 22:-, 2021; PubMed: 34299354; DOI: 10.3390/ijms22147735

Experimental method

X-RAY DIFFRACTION (2.2 Å)