7NRY

Re-refinement of MAPKAP kinase-2/inhibitor complex 3fyj

Summary for 7NRY

• Entry DOI: 10.2210/pdb7nry/pdb
• Descriptor: MAP kinase-activated protein kinase 2, (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: mk-2, mk2, mapkap-2, ser/thr kinase, map kinase, alternative splicing, atp-binding, kinase, nucleotide-binding, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 38411.72

Authors

Croll, T.I.,Read, R.J. (deposition date: 2021-03-04, release date: 2022-02-09, Last modification date: 2024-01-31)

• Primary citation: Croll, T.I.,Read, R.J.; Adaptive Cartesian and torsional restraints for interactive model rebuilding.; Acta Crystallogr D Struct Biol, 77:438-446, 2021; PubMed: 33825704; DOI: 10.1107/S2059798321001145

Experimental method

X-RAY DIFFRACTION (3.8 Å)