7NPG

Crystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide and fragment 22

Summary for 7NPG

• Entry DOI: 10.2210/pdb7npg/pdb
• Descriptor: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), 5-[3-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, ... (7 entities in total)
• Functional Keywords: protein-peptide complex fragment soaking, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30920.33

Authors

Centorrino, F.,Ottmann, C. (deposition date: 2021-02-26, release date: 2022-01-12, Last modification date: 2024-01-31)

• Primary citation: Centorrino, F.,Andlovic, B.,Cossar, P.,Brunsveld, L.,Ottmann, C.; Fragment-based exploration of the 14-3-3/Amot-p130 interface.; Curr Res Struct Biol, 4:21-28, 2022; PubMed: 35036934; DOI: 10.1016/j.crstbi.2021.12.003

Experimental method

X-RAY DIFFRACTION (1.37 Å)