7NN2

Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 41

Summary for 7NN2

Entry DOI	10.2210/pdb7nn2/pdb
Descriptor	14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), 7-(6-azanyl-5-methyl-pyridin-2-yl)-1-benzothiophene-2-carboximidamide, ... (6 entities in total)
Functional Keywords	protein-peptide complex fragment soaking, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	30211.23
Authors	Centorrino, F.,Ottmann, C. (deposition date: 2021-02-24, release date: 2022-01-12, Last modification date: 2024-01-31)
Primary citation	Centorrino, F.,Andlovic, B.,Cossar, P.,Brunsveld, L.,Ottmann, C. Fragment-based exploration of the 14-3-3/Amot-p130 interface. Curr Res Struct Biol, 4:21-28, 2022 Cited by PubMed: 35036934 DOI: 10.1016/j.crstbi.2021.12.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation