7NMV

Crystal structure of beta-2-microglobulin D76Q mutant

This is a non-PDB format compatible entry.

Summary for 7NMV

• Entry DOI: 10.2210/pdb7nmv/pdb
• Descriptor: Beta-2-microglobulin (2 entities in total)
• Functional Keywords: major histocompatibility complex class 1, beta-2-microglobulin, mutant, d76q, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 11892.40

Authors

Guthertz, N. (deposition date: 2021-02-23, release date: 2022-08-03, Last modification date: 2024-01-31)

• Primary citation: Guthertz, N.,van der Kant, R.,Martinez, R.M.,Xu, Y.,Trinh, C.,Iorga, B.I.,Rousseau, F.,Schymkowitz, J.,Brockwell, D.J.,Radford, S.E.; The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.; Proc.Natl.Acad.Sci.USA, 119:e2200468119-e2200468119, 2022; PubMed: 35613051; DOI: 10.1073/pnas.2200468119

Experimental method

X-RAY DIFFRACTION (1.51 Å)