7NLV

WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE II

This is a non-PDB format compatible entry.

Summary for 7NLV

• Entry DOI: 10.2210/pdb7nlv/pdb
• Related: 6GH7 6ZYT
• Descriptor: Streptavidin, 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-((S)-pyrrolidin-3-yl)pentanamide (3 entities in total)
• Functional Keywords: biotin-binding protein, streptavidin, artificial enzyme, beta-barrel, de novo protein
• Biological source: Streptomyces avidinii
• Total number of polymer chains: 4
• Total formula weight: 54899.85

Authors

Nodling, A.R.,Santi, N.,Tsai, Y.H.,Rizkallah, P.,Luk, L.Y.P.,Jin, Y. (deposition date: 2021-02-22, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Nodling, A.R.,Santi, N.,Castillo, R.,Lipka-Lloyd, M.,Jin, Y.,Morrill, L.C.,Swiderek, K.,Moliner, V.,Luk, L.Y.P.; The role of streptavidin and its variants in catalysis by biotinylated secondary amines.; Org.Biomol.Chem., 19:10424-10431, 2021; PubMed: 34825690; DOI: 10.1039/d1ob01947c

Experimental method

X-RAY DIFFRACTION (1.29 Å)