7NJ6

14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1005

Summary for 7NJ6

• Entry DOI: 10.2210/pdb7nj6/pdb
• Related: 7AOG
• Descriptor: 14-3-3 protein sigma, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, 4-[4-(trifluoromethyl)imidazol-1-yl]benzaldehyde, ... (5 entities in total)
• Functional Keywords: 1433, peptide binding protein, peptidyl-prolyl cis-trans isomerase nima-interacting 1
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30702.16

Authors

Wolter, M.,Dijck, L.v.,Cossar, P.J.,Ottmann, C. (deposition date: 2021-02-16, release date: 2021-06-16, Last modification date: 2024-01-31)

• Primary citation: Cossar, P.J.,Wolter, M.,van Dijck, L.,Valenti, D.,Levy, L.M.,Ottmann, C.,Brunsveld, L.; Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.; J.Am.Chem.Soc., 143:8454-8464, 2021; PubMed: 34047554; DOI: 10.1021/jacs.1c03035

Experimental method

X-RAY DIFFRACTION (1.59 Å)