7NJ4

1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core

Summary for 7NJ4

• Entry DOI: 10.2210/pdb7nj4/pdb
• EMDB information: 12372
• Descriptor: Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... (6 entities in total)
• Functional Keywords: influenza, rna polymerase, h1n1, 1918, viral protein, nanobody
• Biological source: Influenza A virus (A/Brevig Mission/1/1918(H1N1)); More
• Total number of polymer chains: 6
• Total formula weight: 297081.59

Authors

Keown, J.R.,Carrique, L.,Fodor, E.,Grimes, J.M. (deposition date: 2021-02-16, release date: 2021-12-01, Last modification date: 2022-02-09)

• Primary citation: Keown, J.R.,Zhu, Z.,Carrique, L.,Fan, H.,Walker, A.P.,Serna Martin, I.,Pardon, E.,Steyaert, J.,Fodor, E.,Grimes, J.M.; Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.; Nat Commun, 13:251-251, 2022; PubMed: 35017564; DOI: 10.1038/s41467-021-27950-w

Experimental method

ELECTRON MICROSCOPY (5.84 Å)