7NIX

14-3-3 sigma with AS160 binding site pT642

Summary for 7NIX

• Entry DOI: 10.2210/pdb7nix/pdb
• Descriptor: 14-3-3 protein sigma, TBC1 domain family member 4, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (5 entities in total)
• Functional Keywords: 1433, tbc1 domain family member 4, peptide-protein complex, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30120.24

Authors

Wolter, M.,Ottmann, C. (deposition date: 2021-02-14, release date: 2021-06-16, Last modification date: 2024-01-31)

• Primary citation: Cossar, P.J.,Wolter, M.,van Dijck, L.,Valenti, D.,Levy, L.M.,Ottmann, C.,Brunsveld, L.; Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.; J.Am.Chem.Soc., 143:8454-8464, 2021; PubMed: 34047554; DOI: 10.1021/jacs.1c03035

Experimental method

X-RAY DIFFRACTION (1.9 Å)