7NFX

Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A

This is a non-PDB format compatible entry.

Summary for 7NFX

• Entry DOI: 10.2210/pdb7nfx/pdb
• EMDB information: 12303
• Descriptor: SRP RNA 7SL, uL30, 60S ribosomal protein L7a, ... (59 entities in total)
• Functional Keywords: signal recognition particle, protein targeting to the er membrane, ribosome
• Biological source: Homo sapiens; More
• Total number of polymer chains: 55
• Total formula weight: 2468070.52

Authors

Jomaa, A.,Lee, J.H.,Shan, S.,Ban, N. (deposition date: 2021-02-08, release date: 2021-06-02)

• Primary citation: Lee, J.H.,Jomaa, A.,Chung, S.,Hwang Fu, Y.H.,Qian, R.,Sun, X.,Hsieh, H.H.,Chandrasekar, S.,Bi, X.,Mattei, S.,Boehringer, D.,Weiss, S.,Ban, N.,Shan, S.O.; Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.; Sci Adv, 7:-, 2021; PubMed: 34020957; DOI: 10.1126/sciadv.abg0942

Experimental method

ELECTRON MICROSCOPY (3.2 Å)