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7NC0

The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer

Summary for 7NC0
Entry DOI10.2210/pdb7nc0/pdb
DescriptorA33 Fab light chain, A33 Fab heavy chain (3 entities in total)
Functional Keywordsmonoclonal antibodies, human a33 fab, colorectal cancer therapy, humanised fab, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains2
Total formula weight46307.73
Authors
Tang, J.,Zhang, C.,Dalby, P.,Kozielski, F. (deposition date: 2021-01-28, release date: 2022-03-02, Last modification date: 2024-01-31)
Primary citationTang, J.,Zhang, C.,Dalby, P.,Kozielski, F.
The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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