7NC0
The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
Summary for 7NC0
Entry DOI | 10.2210/pdb7nc0/pdb |
Descriptor | A33 Fab light chain, A33 Fab heavy chain (3 entities in total) |
Functional Keywords | monoclonal antibodies, human a33 fab, colorectal cancer therapy, humanised fab, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 46307.73 |
Authors | Tang, J.,Zhang, C.,Dalby, P.,Kozielski, F. (deposition date: 2021-01-28, release date: 2022-03-02, Last modification date: 2024-01-31) |
Primary citation | Tang, J.,Zhang, C.,Dalby, P.,Kozielski, F. The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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