7MYH

Ubiquitin variant UbV.k.2 in complex with Ube2k

Summary for 7MYH

• Entry DOI: 10.2210/pdb7myh/pdb
• Descriptor: Ubiquitin-conjugating enzyme E2 K, Ubiquitin variant UbV.k.2, GLYCEROL, ... (4 entities in total)
• Functional Keywords: ubiquitin conjugating enzyme, degradation, ubiquitin variant, inhibitor, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 33055.57

Authors

Middleton, A.J.,Day, C.L.,Teyra, J.,Sidhu, S.S. (deposition date: 2021-05-21, release date: 2021-08-25, Last modification date: 2023-10-18)

• Primary citation: Middleton, A.J.,Teyra, J.,Zhu, J.,Sidhu, S.S.,Day, C.L.; Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.; Acs Chem.Biol., 16:1745-1756, 2021; PubMed: 34397214; DOI: 10.1021/acschembio.1c00445

Experimental method

X-RAY DIFFRACTION (2.394 Å)