7MXL
Complex of Bet v 1 with the Fab fragments of a three antibody cocktail
Summary for 7MXL
Entry DOI | 10.2210/pdb7mxl/pdb |
EMDB information | 24073 |
Descriptor | REGN5713 antibody Fab fragment heavy chain, REGN5713 antibody Fab fragment light chain, Major pollen allergen Bet v 1-A, ... (7 entities in total) |
Functional Keywords | complex, antibody, birch pollen allergen bet v 1, allergen |
Biological source | Homo sapiens More |
Total number of polymer chains | 7 |
Total formula weight | 159713.83 |
Authors | Romero-Hernandez, A.,Franklin, M.C. (deposition date: 2021-05-19, release date: 2021-07-21, Last modification date: 2022-01-19) |
Primary citation | Atanasio, A.,Franklin, M.C.,Kamat, V.,Hernandez, A.R.,Badithe, A.,Ben, L.H.,Jones, J.,Bautista, J.,Yancopoulos, G.D.,Olson, W.,Murphy, A.J.,Sleeman, M.A.,Orengo, J.M. Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response. J.Allergy Clin.Immunol., 149:200-211, 2022 Cited by PubMed: 34126155DOI: 10.1016/j.jaci.2021.05.038 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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