7MTR

CryoEM Structure of Full-Length mGlu2 Bound to Ago-PAM ADX55164 and Glutamate

Summary for 7MTR

Entry DOI	10.2210/pdb7mtr/pdb
EMDB information	23995
Descriptor	Metabotropic glutamate receptor 2, GLUTAMIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	metabotropic glutamate receptor 2 (mglu2) (mglur2), family c g protein-coupled receptor (gpcr), heterotrimeric g protein, cryoem structure, membrane protein, membrane protein-agonist complex, membrane protein/agonist
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	189027.07
Authors	Seven, A.B.,Barros-Alvarez, X.,Skiniotis, G. (deposition date: 2021-05-13, release date: 2021-07-07, Last modification date: 2021-09-08)
Primary citation	Seven, A.B.,Barros-Alvarez, X.,de Lapeyriere, M.,Papasergi-Scott, M.M.,Robertson, M.J.,Zhang, C.,Nwokonko, R.M.,Gao, Y.,Meyerowitz, J.G.,Rocher, J.P.,Schelshorn, D.,Kobilka, B.K.,Mathiesen, J.M.,Skiniotis, G. G-protein activation by a metabotropic glutamate receptor. Nature, 595:450-454, 2021 Cited by PubMed: 34194039 DOI: 10.1038/s41586-021-03680-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation