7MSV

Solution Structure of Berberine Bound to a dGMP Fill-in G-Quadruplex in the PDGFR-b Promoter

Summary for 7MSV

• Entry DOI: 10.2210/pdb7msv/pdb
• NMR Information: BMRB: 30907
• Descriptor: DNA (5'-D(*AP*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3'), 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, BERBERINE (3 entities in total)
• Functional Keywords: g-quadruplex, promoter, guanine metabolite, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 7029.83

Authors

Wang, K.B.,Dickerhoff, J.,Yang, D. (deposition date: 2021-05-12, release date: 2021-10-20, Last modification date: 2024-05-15)

• Primary citation: Wang, K.B.,Dickerhoff, J.,Yang, D.; Solution Structure of Ternary Complex of Berberine Bound to a dGMP-Fill-In Vacancy G-Quadruplex Formed in the PDGFR-beta Promoter.; J.Am.Chem.Soc., 143:16549-16555, 2021; PubMed: 34586799; DOI: 10.1021/jacs.1c06200

Experimental method

SOLUTION NMR