7MP1
CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1,5-DI-METHYLENEBISPHOSPHONATE INOSITOL TETRAKISPHOSPHATE (1,5-PCP-IP4)
Summary for 7MP1
Entry DOI | 10.2210/pdb7mp1/pdb |
Descriptor | S-arrestin, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid) (3 entities in total) |
Functional Keywords | gpcr, rhodopsin, phototransduction, inositol, 5pp-ip5, ip7, protein binding |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 4 |
Total formula weight | 185419.37 |
Authors | Sander, C.L.,Palczewski, K.,Kiser, P.D. (deposition date: 2021-05-04, release date: 2021-10-13, Last modification date: 2023-10-18) |
Primary citation | Sander, C.L.,Luu, J.,Kim, K.,Furkert, D.,Jang, K.,Reichenwallner, J.,Kang, M.,Lee, H.J.,Eger, B.T.,Choe, H.W.,Fiedler, D.,Ernst, O.P.,Kim, Y.J.,Palczewski, K.,Kiser, P.D. Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure, 30:263-277.e5, 2022 Cited by PubMed: 34678158DOI: 10.1016/j.str.2021.10.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
Download full validation report