7MOJ

Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with a metaphosphate intermediate

Summary for 7MOJ

Entry DOI	10.2210/pdb7moj/pdb
Descriptor	Tyrosine-protein phosphatase DSP1, PHOSPHITE ION (3 entities in total)
Functional Keywords	inositol, inositol pyrophosphate, transferase, hydrolase, cell-signaling, phosphatase, substrate recognition, reaction mechanism, intermediate, phosphate, metaphosphate, molecular dynamic simulation, self-activation, catalytic water
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	2
Total formula weight	39443.48
Authors	Wang, H.,Shears, S.B. (deposition date: 2021-05-01, release date: 2022-03-02, Last modification date: 2022-05-11)
Primary citation	Wang, H.,Perera, L.,Jork, N.,Zong, G.,Riley, A.M.,Potter, B.V.L.,Jessen, H.J.,Shears, S.B. A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nat Commun, 13:2231-2231, 2022 Cited by PubMed: 35468885 DOI: 10.1038/s41467-022-29673-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation