7MMZ

Crystal Structure of Acetyl-coenzyme A synthetase from Legionella pneumophila Philadelphia 1 in complex with ethyl-AMP

Summary for 7MMZ

Entry DOI	10.2210/pdb7mmz/pdb
Descriptor	Acetyl-coenzyme A synthetase, 5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	ssgcid, acetyl-coenzyme a synthetase, acs-1, legionella pneumophila, structural genomics, seattle structural genomics center for infectious disease, ligase
Biological source	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Total number of polymer chains	1
Total formula weight	71068.82
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2021-04-30, release date: 2021-05-26, Last modification date: 2023-10-25)
Primary citation	DeBouver, N.D.,Bolejack, M.J.,Esan, T.E.,Krysan, D.J.,Hagen, T.J.,Abendroth, J. Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor. Acta Crystallogr.,Sect.F, 2023 Cited by PubMed: 37223974 DOI: 10.1107/S2053230X23003801 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation