7MKV

Engineered PLP-dependent decarboxylative aldolase from Aspergillus flavus, UstD2.0, bound as the internal aldimine

Summary for 7MKV

• Entry DOI: 10.2210/pdb7mkv/pdb
• Descriptor: Cysteine desulfurase-like protein ustD (2 entities in total)
• Functional Keywords: internal aldimine, plp, enamine, directed evolution, lyase, transferase
• Biological source: Aspergillus flavus
• Total number of polymer chains: 3
• Total formula weight: 148785.41

Authors

Ellis, J.M.,Buller, A.R.,Bingman, C.A. (deposition date: 2021-04-27, release date: 2022-05-04)

• Primary citation: Ellis, J.M.,Campbell, M.E.,Kumar, P.,Geunes, E.P.,Bingman, C.A.,Buller, A.R.; Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction; Nat Catal, 5:136-143, 2022; DOI: 10.1038/s41929-022-00743-0

Experimental method

X-RAY DIFFRACTION (2.25 Å)