7MJW

Methylated MiaB in the complex with 5'-deoxyadenosine, methionine and RNA

Summary for 7MJW

• Entry DOI: 10.2210/pdb7mjw/pdb
• Descriptor: tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, RNA (5'-R(*GP*GP*AP*CP*UP*GP*AP*AP*(MIA)P*AP*UP*CP*C)-3'), FE3-S4 methylated cluster, ... (8 entities in total)
• Functional Keywords: trna-2-methylthio-n(6)-dimethylallyladenosine synthase, transferase, transferase-rna complex, transferase/rna
• Biological source: Bacteroides uniformis; More
• Total number of polymer chains: 4
• Total formula weight: 113214.74

Authors

Esakova, O.A.,Grove, T.L.,Yennawar, N.H.,Arcinas, A.J.,Wang, B.,Krebs, C.,Almo, S.C.,Booker, S.J. (deposition date: 2021-04-20, release date: 2021-09-15, Last modification date: 2023-10-18)

• Primary citation: Esakova, O.A.,Grove, T.L.,Yennawar, N.H.,Arcinas, A.J.,Wang, B.,Krebs, C.,Almo, S.C.,Booker, S.J.; Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.; Nature, 597:566-570, 2021; PubMed: 34526715; DOI: 10.1038/s41586-021-03904-6

Experimental method

X-RAY DIFFRACTION (1.4 Å)