7MIV

Mouse CTPS2-I250T bound to inhibitor R80

Summary for 7MIV

Entry DOI	10.2210/pdb7miv/pdb
EMDB information	23866
Descriptor	CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	glutaminase, amidoligase, nucleotide metabolism, ligase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	4
Total formula weight	266885.41
Authors	Lynch, E.M.,Dimattia, M.A.,Kollman, J.M. (deposition date: 2021-04-17, release date: 2021-10-13, Last modification date: 2024-05-29)
Primary citation	Lynch, E.M.,DiMattia, M.A.,Albanese, S.,van Zundert, G.C.P.,Hansen, J.M.,Quispe, J.D.,Kennedy, M.A.,Verras, A.,Borrelli, K.,Toms, A.V.,Kaila, N.,Kreutter, K.D.,McElwee, J.J.,Kollman, J.M. Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34583994 DOI: 10.1073/pnas.2107968118 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation