7MFB

Crystal structure of antibody 10E8v4 Fab - light chain H31F variant

Summary for 7MFB

• Entry DOI: 10.2210/pdb7mfb/pdb
• Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain (3 entities in total)
• Functional Keywords: monoclonal antibody 10e8, mper, cis-trans isomerization, size-exclusion chromatography, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47518.90

Authors

Kwon, Y.D.,Kwong, P.D. (deposition date: 2021-04-08, release date: 2021-07-14, Last modification date: 2023-10-18)

• Primary citation: Do Kwon, Y.,Wang, X.E.,Bender, M.F.,Yang, R.,Li, Y.,McKee, K.,Rawi, R.,O'Dell, S.,Schneck, N.A.,Shaddeau, A.,Zhang, B.,Arnold, F.J.,Connors, M.,Doria-Rose, N.A.,Kwong, P.D.,Lei, Q.P.; Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.; Antibodies, 10:-, 2021; PubMed: 34200826; DOI: 10.3390/antib10020023

Experimental method

X-RAY DIFFRACTION (1.74 Å)