7ME8
The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-Q114 rotamer conformation at 1.60 Angstrom resolution
Summary for 7ME8
Entry DOI | 10.2210/pdb7me8/pdb |
Related | 4KKX 4WX2 4Y6G 4ZQC 5BW6 7KU9 7LY8 7M2L 7M3S |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (8 entities in total) |
Functional Keywords | inhibitor, internal aldimine, lyase |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 72385.16 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-04-06, release date: 2021-10-13, Last modification date: 2023-10-18) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J. The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-Q114 rotamer conformation at 1.60 Angstrom resolution. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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