7MD7
Crystal structure of the Thermus thermophilus 70S ribosome in complex with triphenylphosphonium analog of chloramphenicol CAM-C4-TPP and protein Y (YfiA) at 2.80A resolution
This is a non-PDB format compatible entry.
Summary for 7MD7
Entry DOI | 10.2210/pdb7md7/pdb |
Descriptor | 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (60 entities in total) |
Functional Keywords | chloramphenicol, antibiotic, 70s ribosome, translation inhibitor, peptidyl transferase center, nascent peptide exit tunnel, ribosome |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 106 |
Total formula weight | 4428454.05 |
Authors | Chen, C.-W.,Pavlova, J.A.,Lukianov, D.A.,Tereshchenkov, A.G.,Makarov, G.I.,Khairullina, Z.Z.,Tashlitsky, V.N.,Paleskava, A.,Konevega, A.L.,Bogdanov, A.A.,Osterman, I.A.,Sumbatyan, N.V.,Polikanov, Y.S. (deposition date: 2021-04-03, release date: 2021-04-21, Last modification date: 2023-11-15) |
Primary citation | Chen, C.W.,Pavlova, J.A.,Lukianov, D.A.,Tereshchenkov, A.G.,Makarov, G.I.,Khairullina, Z.Z.,Tashlitsky, V.N.,Paleskava, A.,Konevega, A.L.,Bogdanov, A.A.,Osterman, I.A.,Sumbatyan, N.V.,Polikanov, Y.S. Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics, 10:-, 2021 Cited by PubMed: 33916420DOI: 10.3390/antibiotics10040390 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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