7M32

Dihydropyrimidine Dehydrogenase (DPD) C671A Mutant Soaked with Uracil and NADPH Anaerobically

Summary for 7M32

Entry DOI	10.2210/pdb7m32/pdb
Descriptor	Dihydropyrimidine dehydrogenase [NADP(+)], IRON/SULFUR CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... (9 entities in total)
Functional Keywords	dihydropyrimidine dehydrogenase, dpd, mutant, uracil, flavin, soaking, ligand, fmn, fad, flavoprotein, oxidoreductase
Biological source	Sus scrofa (Pig)
Total number of polymer chains	4
Total formula weight	457891.01
Authors	Butrin, A.,Beaupre, B.,Forouzesh, D.,Liu, D.,Moran, G. (deposition date: 2021-03-18, release date: 2021-06-09, Last modification date: 2023-10-18)
Primary citation	Beaupre, B.A.,Forouzesh, D.C.,Butrin, A.,Liu, D.,Moran, G.R. Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase. Biochemistry, 60:1764-1775, 2021 Cited by PubMed: 34032117 DOI: 10.1021/acs.biochem.1c00243 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation