7M07
Pre-catalytic ternary complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP
Summary for 7M07
Entry DOI | 10.2210/pdb7m07/pdb |
Descriptor | DNA polymerase lambda, DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... (10 entities in total) |
Functional Keywords | nonhomologous end-joining, base excision repair, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 45798.03 |
Authors | Kaminski, A.M.,Bebenek, K.,Pedersen, L.C.,Kunkel, T.A. (deposition date: 2021-03-10, release date: 2022-03-16, Last modification date: 2023-10-25) |
Primary citation | Kaminski, A.M.,Chiruvella, K.K.,Ramsden, D.A.,Bebenek, K.,Kunkel, T.A.,Pedersen, L.C. Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining. Nat Commun, 13:3806-3806, 2022 Cited by PubMed: 35778389DOI: 10.1038/s41467-022-31278-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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