7LYB
Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c
Summary for 7LYB
Entry DOI | 10.2210/pdb7lyb/pdb |
EMDB information | 23590 23591 23592 |
Descriptor | Histone H3.1, ZINC ION, Histone H4, ... (10 entities in total) |
Functional Keywords | nucleosome core particle, chromatin, brca1, bard1, ubch5c, dna repair, dna double-strand break, homologous recombination, 53bp1, structural protein-dna complex, structural protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 13 |
Total formula weight | 241828.64 |
Authors | |
Primary citation | Hu, Q.,Botuyan, M.V.,Zhao, D.,Cui, G.,Mer, E.,Mer, G. Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Nature, 596:438-443, 2021 Cited by PubMed: 34321665DOI: 10.1038/s41586-021-03716-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.28 Å) |
Structure validation
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