7LQV

Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike

Summary for 7LQV

• Entry DOI: 10.2210/pdb7lqv/pdb
• EMDB information: 23489 23490
• Descriptor: Spike glycoprotein, 4-8 Heavy Chain, 4-8 Light chain, ... (4 entities in total)
• Functional Keywords: covid, covid19, sars-cov2, prefusion, neutralizing, ntd, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 9
• Total formula weight: 512635.48

Authors

Gorman, J.,Rapp, M.,Kwong, P.D.,Shapiro, L. (deposition date: 2021-02-15, release date: 2021-03-24)

• Primary citation: Cerutti, G.,Guo, Y.,ZHou, T.,Gorman, J.,Lee, M.,Rapp, M.,Reddem, E.R.,Yu, J.,Bahna, F.,Bimela, J.,Huang, Y.,Katsamba, PS.,Liu, L.,Nair, M.S.,Rawi, R.,Olia, A.S.,Wang, P.,Zhang, B.,Chuang, G.Y.,Ho, D.D.,Sheng, Z.,Kwong, P.D.,Shapiro, L.; Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite; Cell Host Microbe, 2021; DOI: 10.1016/j.chom.2021.03.005

Experimental method

ELECTRON MICROSCOPY (3.25 Å)