7LO0
Structure of human ASF1a in complex with a TLK2 peptide
Summary for 7LO0
Entry DOI | 10.2210/pdb7lo0/pdb |
Descriptor | Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2 (3 entities in total) |
Functional Keywords | histone chaperone, kinase, docking, nucleosome assembly, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 24 |
Total formula weight | 182635.60 |
Authors | Simon, B.,Calderwood, D.,Turk, B.E.,Boggon, T.J. (deposition date: 2021-02-08, release date: 2022-02-16, Last modification date: 2023-10-18) |
Primary citation | Simon, B.,Lou, H.J.,Huet-Calderwood, C.,Shi, G.,Boggon, T.J.,Turk, B.E.,Calderwood, D.A. Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. Nat Commun, 13:749-749, 2022 Cited by PubMed: 35136069DOI: 10.1038/s41467-022-28427-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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