7LNW

I146A mutant of the isopentenyl phosphate kinase from Candidatus methanomethylophilus alvus

Summary for 7LNW

Entry DOI	10.2210/pdb7lnw/pdb
Descriptor	Isopentenyl phosphate kinase, ADENOSINE-5'-DIPHOSPHATE, [(~{Z})-5-[(azanylidene-$l^{4}-azanylidene)amino]-3-methyl-pent-2-enyl] dihydrogen phosphate, ... (4 entities in total)
Functional Keywords	phosphotransferase atp biocatalysis isoprenoids enzyme promiscuity, transferase
Biological source	Candidatus Methanomethylophilus alvus
Total number of polymer chains	2
Total formula weight	62281.01
Authors	Thomas, L.M.,Singh, S.,Johnson, B.P. (deposition date: 2021-02-08, release date: 2021-12-22, Last modification date: 2024-04-03)
Primary citation	Johnson, B.P.,Kumar, V.,Scull, E.M.,Thomas, L.M.,Bourne, C.R.,Singh, S. Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17:85-102, 2022 Cited by PubMed: 34905349 DOI: 10.1021/acschembio.1c00655 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation