7LH9
Crystal structure of BRPF2 PWWP domain in complex with DNA
Summary for 7LH9
Entry DOI | 10.2210/pdb7lh9/pdb |
Descriptor | Bromodomain-containing protein 1, DNA (2 entities in total) |
Functional Keywords | brpf2, pwwp, structural genomics, structural genomics consortium, sgc, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 86542.48 |
Authors | Zhang, M.,Lei, M.,Qin, S.,Dong, A.,Yang, A.,Li, Y.,Loppnau, P.,Hughes, T.R.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Liu, J.,Structural Genomics Consortium (SGC) (deposition date: 2021-01-21, release date: 2021-02-17, Last modification date: 2023-10-18) |
Primary citation | Zhang, M.,Lei, M.,Qin, S.,Dong, A.,Yang, A.,Li, Y.,Loppnau, P.,Hughes, T.R.,Min, J.,Liu, Y. Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains. Biochim Biophys Acta Gene Regul Mech, 1864:194688-194688, 2021 Cited by PubMed: 33556623DOI: 10.1016/j.bbagrm.2021.194688 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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