7LCI

PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex

Summary for 7LCI

• Entry DOI: 10.2210/pdb7lci/pdb
• Related: 6X1A
• EMDB information: 23274
• Descriptor: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• Functional Keywords: gpcr, small molecule agonist, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 146792.65

Authors

Belousoff, M.J.,Johnson, R.M.,Drulyte, I.,Yu, L.,Kotecha, A.,Danev, R.,Wootten, D.,Zhang, X.,Sexton, P.M. (deposition date: 2021-01-11, release date: 2021-01-20, Last modification date: 2021-09-15)

• Primary citation: Zhang, X.,Johnson, R.M.,Drulyte, I.,Yu, L.,Kotecha, A.,Danev, R.,Wootten, D.,Sexton, P.M.,Belousoff, M.J.; Evolving cryo-EM structural approaches for GPCR drug discovery.; Structure, 29:963-, 2021; PubMed: 33957078; DOI: 10.1016/j.str.2021.04.008

Experimental method

ELECTRON MICROSCOPY (2.9 Å)