7L78

H235C variant of Yeast Ferrochelatase

Summary for 7L78

Entry DOI	10.2210/pdb7l78/pdb
Descriptor	Ferrochelatase, mitochondrial, CHOLIC ACID (3 entities in total)
Functional Keywords	ferrochelatase, heme biosynthesis, yeast, lyase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	2
Total formula weight	81487.12
Authors	Lanzilotta, W.N.,Medlock, A.E. (deposition date: 2020-12-27, release date: 2021-11-24, Last modification date: 2023-10-18)
Primary citation	Dietz, J.V.,Willoughby, M.M.,Piel III, R.B.,Ross, T.A.,Bohovych, I.,Addis, H.G.,Fox, J.L.,Lanzilotta, W.N.,Dailey, H.A.,Wohlschlegel, J.A.,Reddi, A.R.,Medlock, A.E.,Khalimonchuk, O. Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase. Redox Biol, 46:102125-102125, 2021 Cited by PubMed: 34517185 DOI: 10.1016/j.redox.2021.102125 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation