7L0C

Ligand-free PTP1B T177G

Summary for 7L0C

Entry DOI	10.2210/pdb7l0c/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 1 (2 entities in total)
Functional Keywords	protein tyrosine phosphatase, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	37295.55
Authors	Shen, R.D.,Hengge, A.C.,Johnson, S.J. (deposition date: 2020-12-11, release date: 2021-05-12, Last modification date: 2023-10-18)
Primary citation	Shen, R.,Crean, R.M.,Johnson, S.J.,Kamerlin, S.C.L.,Hengge, A.C. Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases. Jacs Au, 1:646-659, 2021 Cited by PubMed: 34308419 DOI: 10.1021/jacsau.1c00054 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation