7KYL

Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80

Summary for 7KYL

• Entry DOI: 10.2210/pdb7kyl/pdb
• Descriptor: POWV-80 Fab heavy chain, POWV-80 Fab light chain, Envelope protein domain III, ... (6 entities in total)
• Functional Keywords: neutralizing antibody, tick-borne flavivirus, domain iii, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Powassan virus; More
• Total number of polymer chains: 6
• Total formula weight: 118877.44

Authors

Errico, J.M.,Nelson, C.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-12-08, release date: 2021-04-07, Last modification date: 2023-10-18)

• Primary citation: VanBlargan, L.A.,Errico, J.M.,Kafai, N.M.,Burgomaster, K.E.,Jethva, P.N.,Broeckel, R.M.,Meade-White, K.,Nelson, C.A.,Himansu, S.,Wang, D.,Handley, S.A.,Gross, M.L.,Best, S.M.,Pierson, T.C.,Fremont, D.H.,Diamond, M.S.; Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.; J.Exp.Med., 218:-, 2021; PubMed: 33831142; DOI: 10.1084/jem.20210174

Experimental method

X-RAY DIFFRACTION (2 Å)