7KPN

Adeno-associated virus serotype 5 in complex with the cellular receptor AAVR at 2.5 Angstroms resolution, AAV5 AAVR

Summary for 7KPN

• Entry DOI: 10.2210/pdb7kpn/pdb
• Related: 7KP3
• EMDB information: 22987 22988
• Descriptor: Dyslexia-associated protein KIAA0319-like protein, Capsid protein (2 entities in total)
• Functional Keywords: aav5, aav, aav-5, aavr, adeno associated virus, pkd domain, virus like particle, parvovirus, virus, gene therapy, receptor, adeno-associated virus receptor, pkd1, pkd
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 102548.95

Authors

Silveria, M.,Chapman, M.S. (deposition date: 2020-11-12, release date: 2020-12-16, Last modification date: 2024-03-06)

• Primary citation: Silveria, M.A.,Large, E.E.,Zane, G.M.,White, T.A.,Chapman, M.S.; The Structure of an AAV5-AAVR Complex at 2.5 angstrom Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors.; Viruses, 12:-, 2020; PubMed: 33218165; DOI: 10.3390/v12111326

Experimental method

ELECTRON MICROSCOPY (2.5 Å)