7KH0

Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex

Summary for 7KH0

• Entry DOI: 10.2210/pdb7kh0/pdb
• EMDB information: 22872
• Descriptor: Vasopressin V2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-3, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short fusion, ... (7 entities in total)
• Functional Keywords: arginine vasopressin avp, gs, signaling complex, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 7
• Total formula weight: 173940.97

Authors

Wang, L.,Xu, J.,Gao, S.,Sun, D.,Liu, H.,Liu, Z.,Du, Y.,Zhang, C. (deposition date: 2020-10-19, release date: 2021-05-26, Last modification date: 2023-03-29)

• Primary citation: Wang, L.,Xu, J.,Cao, S.,Sun, D.,Liu, H.,Lu, Q.,Liu, Z.,Du, Y.,Zhang, C.; Cryo-EM structure of the AVP-vasopressin receptor 2-G s signaling complex.; Cell Res., 31:932-934, 2021; PubMed: 33664408; DOI: 10.1038/s41422-021-00483-z

Experimental method

ELECTRON MICROSCOPY (2.8 Å)