7KET

Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein

Summary for 7KET

Entry DOI	10.2210/pdb7ket/pdb
Descriptor	Immunoglobulin gamma, kappa light chain, Immunoglobulin gamma, heavy chain Fd fragment, Factor H binding protein, ... (4 entities in total)
Functional Keywords	human, antibody, fab, meningococcal vaccine, factor h binding protein, complex, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	76828.60
Authors	Beernink, P.T.,Sands, N. (deposition date: 2020-10-12, release date: 2021-06-09, Last modification date: 2023-10-18)
Primary citation	Sands, N.A.,Beernink, P.T. Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site. Plos Pathog., 17:e1009655-e1009655, 2021 Cited by PubMed: 34125873 DOI: 10.1371/journal.ppat.1009655 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation