7KE1

Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein

Summary for 7KE1

Entry DOI	10.2210/pdb7ke1/pdb
Descriptor	Immunoglobulin gamma, kappa light chain, Immunoglobulin gamma, heavy chain Fd fragment, SULFATE ION, ... (7 entities in total)
Functional Keywords	human, antibody, fab, meningococcal vaccine, factor h binding protein, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	98253.46
Authors	Beernink, P.T.,Sands, N. (deposition date: 2020-10-09, release date: 2021-06-09, Last modification date: 2024-04-03)
Primary citation	Sands, N.A.,Beernink, P.T. Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site. Plos Pathog., 17:e1009655-e1009655, 2021 Cited by PubMed: 34125873 DOI: 10.1371/journal.ppat.1009655 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation