7KBN

1.60 Angstrom resolution crystal structure of the beta-Q114A mutant of Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site

Summary for 7KBN

• Entry DOI: 10.2210/pdb7kbn/pdb
• Related: 4HPJ 4KKX 6DUC 6O1H 6VFD 6XE3
• Descriptor: Tryptophan synthase alpha chain, CESIUM ION, Tryptophan synthase beta chain, ... (11 entities in total)
• Functional Keywords: inhibitor, tryptophan synthase, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 75211.65

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-10-02, release date: 2021-10-13, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; 1.60 Angstrom resolution crystal structure of the beta-Q114A mutant of Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)