7KAN
Cryo-EM structure of the Sec complex from T. lanuginosus, Sec62-lacking mutant (Delta Sec62)
Summary for 7KAN
| Entry DOI | 10.2210/pdb7kan/pdb |
| EMDB information | 22776 |
| Descriptor | Protein transport channel Sec61 complex, alpha subunit (Sec61), Protein transport channel Sec61 complex, gamma subunit (Sss1), Protein transport channel Sec61 complex, beta subunit (Sbh1), ... (7 entities in total) |
| Functional Keywords | sec61, translocon, endoplasmic reticulum, protein translocation, sec62, sec63, channel, protein transport |
| Biological source | Thermomyces lanuginosus More |
| Total number of polymer chains | 6 |
| Total formula weight | 205265.39 |
| Authors | Itskanov, S.,Park, E. (deposition date: 2020-10-01, release date: 2021-02-03, Last modification date: 2024-03-06) |
| Primary citation | Itskanov, S.,Kuo, K.M.,Gumbart, J.C.,Park, E. Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62. Nat.Struct.Mol.Biol., 28:162-172, 2021 Cited by PubMed: 33398175DOI: 10.1038/s41594-020-00541-x PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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