7K6Q

Active state Dot1 bound to the H4K16ac nucleosome

Summary for 7K6Q

• Entry DOI: 10.2210/pdb7k6q/pdb
• EMDB information: 22691 22692 22693 22694 22695
• Descriptor: Histone H3.2, Histone H4, Histone H2A type 1, ... (9 entities in total)
• Functional Keywords: structural protein/dna/transferase, transferase, structural protein-dna-transferase complex
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 12
• Total formula weight: 233803.35

Authors

Valencia-Sanchez, M.I.,De Ioannes, P.E.,Miao, W.,Truong, D.M.,Lee, R.,Armache, J.-P.,Boeke, J.D.,Armache, K.-J. (deposition date: 2020-09-21, release date: 2021-02-10)

• Primary citation: Valencia-Sanchez, M.I.,De Ioannes, P.,Wang, M.,Truong, D.M.,Lee, R.,Armache, J.P.,Boeke, J.D.,Armache, K.J.; Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.; Science, 371:-, 2021; PubMed: 33479126; DOI: 10.1126/science.abc6663

Experimental method

ELECTRON MICROSCOPY (3.1 Å)