7JYA

Crystal structure of E3 ligase in complex with peptide

Summary for 7JYA

• Entry DOI: 10.2210/pdb7jya/pdb
• Descriptor: Protein fem-1 homolog C, ASN-ARG-ARG-ARG-ARG-TRP-ARG-GLU-ARG-GLN-ARG, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: ups, ubiquitin, e3 ligase, protein degradation, structural genomics, structural genomics consortium, sgc, ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 128304.13

Authors

Yan, X.,Dong, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Min, J.R.,Dong, C.,Structural Genomics Consortium (SGC) (deposition date: 2020-08-30, release date: 2020-10-14, Last modification date: 2023-10-18)

• Primary citation: Yan, X.,Wang, X.,Li, Y.,Zhou, M.,Li, Y.,Song, L.,Mi, W.,Min, J.,Dong, C.; Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron.; Nat.Chem.Biol., 17:263-271, 2021; PubMed: 33398170; DOI: 10.1038/s41589-020-00703-4

Experimental method

X-RAY DIFFRACTION (2.46 Å)