7JVO
Importin alpha bound to the C-terminus of ACE2
Summary for 7JVO
Entry DOI | 10.2210/pdb7jvo/pdb |
Descriptor | Importin subunit alpha-1, ARG-LYS-LYS-LYS-ASN-LYS-ALA (3 entities in total) |
Functional Keywords | importin, karyopherin, ace2, transport protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 56962.40 |
Authors | Forwood, J.K.,Cross, E.M.,Tsimbalyuk, S. (deposition date: 2020-08-22, release date: 2020-10-14, Last modification date: 2023-10-18) |
Primary citation | Tu, W.J.,McCuaig, R.D.,Melino, M.,Rawle, D.J.,Le, T.T.,Yan, K.,Suhrbier, A.,Johnston, R.L.,Koufariotis, L.T.,Waddell, N.,Cross, E.M.,Tsimbalyuk, S.,Bain, A.,Ahern, E.,Collinson, N.,Phipps, S.,Forwood, J.K.,Seddiki, N.,Rao, S. Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication. Cell Discov, 7:37-37, 2021 Cited by PubMed: 34031383DOI: 10.1038/s41421-021-00279-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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